The Cassandra Crossing can be an all-star disaster spectacular notification of those terrifying odyssey of 1000 doomed passengers trapped aboard an train that is plague-infested. A terrorist infected with a lethal virus planks the Stockholm into Geneva Express and reveals most aboard into the disorder. Colonel Mackenzie (Burt Lancaster) is called in to manage the situation and locates out Dr. Chamberlain (Richard Harris) who is onboard the train. At which it'll dive into oblivion mackenzie decides to reroute the train into the Cassandra Crossing. But passengers miraculously begin to recover and Chamberlain must race against the time to disconnect the cars.