"Lowriders vs. Zombies from Space" is a comedy about lowriders and zombies from space set in the city of San Antonio, Texas. "B" low-budget movies made in the 1980s and 1990s are a big influence on this movie, but it also has a modern twist on the old movies. They are going to go to a dance that night. This story is about a group of friends and lowriders who are going to go together. In the middle of the dance, a strange alien substance is added, and it infects several people, making them into alien zombies. After that, everything goes crazy inside and outside of the dance hall. Lowriders have to use their cars as weapons to fight off the alien zombies.